Table 5.
ICU mortality and each glycemic condition with/without hypoalbuminemia
| Glycemic conditions | Odds | 95% CI | p value |
|---|---|---|---|
| Hypo-G | 3.503 | 1.7820–6.9351 | 0.0003 |
| Inter-G | 1.175 | 0.7324–1.9093 | 0.5083 |
| Hyper-G | 1.756 | 1.0150–3.1443 | 0.0439 |
| Hypo-G + Hypo-A | 5.065 | 2.1664–12.498 | 0.0002 |
| Inter-G + Hypo-A | 1.925 | 1.1487–3.2115 | 0.0131 |
| Hyper-G + Hypo-A | 0.980 | 0.4349–2.0552 | 0.9591 |
| aInter-G + Nonhypo-A | 0.349 | 0.1897–0.6152 | 0.0002 |
| Other parameters | |||
| APACHE II score | 1.116 | 1.0753–1.1611 | < 0.0001 |
| SOFA score | 1.256 | 1.1559–1.3737 | < 0.0001 |
| Hypo-A | 3.243 | 1.9774–5.3957 | < 0.0001 |
Odds ratio of each glycemic condition, SOFA score, and/or hypoalbuminemia, respectively, were independently calculated by a single logistic regression analysis of the initial laboratory data at the time of admission due to multicollinearity. In each Hypo-A, Inter-G + Nonhypo-A, Hypo-G + Hypo-A, Inter-G + Hypo-A and Hyper-G + Hypo-A group, there were some cases which were included in more than one group
Hypo-G hypoglycemia group (blood glucose level < 80 mg/dl), Hyper-G hyperglycemia group (blood glucose level ≥ 200 mg/dl), Inter-G intermediate glycemia group (blood glucose level = 80–199 mg/dl), Hypo-A hypoalbuminemia (blood albumin < 2.8 mg/dl), Nonhypo-A non-hypoalbuminemia (blood albumin ≥ 2.8 mg/dl or more), Inter-G + Nonhypo-A patients with a glycemic level between 80 and 199 mg/dl and blood albumin 2.8 mg/dl or more, Hypo-G + Hypo-A patients with a glycemic level < 80 mg/dl and blood albumin < 2.8 mg/dl, Inter-G + Hypo-A patients with a glycemic level between 80 and 199 mg/dl and blood albumin < 2.8 mg/dl, Hyper-G + Hypo-A patients with a glycemic level ≥ 200 mg/dl and blood albumin < 2.8 mg/dl, SOFA sequential organ failure assessment
Odds ratio was higher in the “Hypo-G + Hypo-A” group than any other glycemic condition
aInter-G + Nonhypo-A: Patients classified in this group showed a lower odds ratio for mortality