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. 2019 Feb 7;14(4):539–548. doi: 10.1007/s11739-019-02034-2

Table 5.

ICU mortality and each glycemic condition with/without hypoalbuminemia

Glycemic conditions Odds 95% CI p value
Hypo-G 3.503 1.7820–6.9351 0.0003
Inter-G 1.175 0.7324–1.9093 0.5083
Hyper-G 1.756 1.0150–3.1443 0.0439
Hypo-G + Hypo-A 5.065 2.1664–12.498 0.0002
Inter-G + Hypo-A 1.925 1.1487–3.2115 0.0131
Hyper-G + Hypo-A 0.980 0.4349–2.0552 0.9591
aInter-G + Nonhypo-A 0.349 0.1897–0.6152 0.0002
Other parameters
 APACHE II score 1.116 1.0753–1.1611 < 0.0001
 SOFA score 1.256 1.1559–1.3737 < 0.0001
 Hypo-A 3.243 1.9774–5.3957 < 0.0001

Odds ratio of each glycemic condition, SOFA score, and/or hypoalbuminemia, respectively, were independently calculated by a single logistic regression analysis of the initial laboratory data at the time of admission due to multicollinearity. In each Hypo-A, Inter-G + Nonhypo-A, Hypo-G + Hypo-A, Inter-G + Hypo-A and Hyper-G + Hypo-A group, there were some cases which were included in more than one group

Hypo-G hypoglycemia group (blood glucose level < 80 mg/dl), Hyper-G hyperglycemia group (blood glucose level ≥ 200 mg/dl), Inter-G intermediate glycemia group (blood glucose level = 80–199 mg/dl), Hypo-A hypoalbuminemia (blood albumin < 2.8 mg/dl), Nonhypo-A non-hypoalbuminemia (blood albumin ≥ 2.8 mg/dl or more), Inter-G + Nonhypo-A patients with a glycemic level between 80 and 199 mg/dl and blood albumin 2.8 mg/dl or more, Hypo-G + Hypo-A patients with a glycemic level < 80 mg/dl and blood albumin < 2.8 mg/dl, Inter-G + Hypo-A patients with a glycemic level between 80 and 199 mg/dl and blood albumin < 2.8 mg/dl, Hyper-G + Hypo-A patients with a glycemic level ≥ 200 mg/dl and blood albumin < 2.8 mg/dl, SOFA sequential organ failure assessment

Odds ratio was higher in the “Hypo-G + Hypo-A” group than any other glycemic condition

aInter-G + Nonhypo-A: Patients classified in this group showed a lower odds ratio for mortality