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. 2019 May 27;9:7868. doi: 10.1038/s41598-019-44301-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Microbiome analyses of hookworm-infected hamsters. (A) Beta-diversity between hookworm-infected and uninfected hamsters. Principal Coordinate analysis of beta-diversity between samples is presented as calculated in QIIME2:2018.4. The unweighted unifrac metric was used to calculate distances between samples. The percent of total variation explained by each PCoA axis is given in parentheses. Red tones = infected; blue tones = uninfected. Experiments A and B are shown separately for each. Each dot represents an individual sample. (B) Alpha-diversity between hookworm-infected and uninfected hamsters. Alpha diversity analysis using Faith’s Phylogenetic Diversity (PD) as calculated in QIIME2:2018.4. Boxes indicate the 25th and 75th percentiles (first and third quartiles) for uninfected (left) and infected (right) hamsters. The horizontal line within the box denotes the median. Whiskers show the range of the data excluding outliers (which are shown as gray dots) that fell more than 1.5 times the interquartile range.