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. 2019 May 27;9:7888. doi: 10.1038/s41598-019-44214-2

Table 3.

Predictors of AF development by Multivariate Cox regression Analysis. Model 1 was adjusted for sex and age; model 2 included GFR and model 3 also LVH and carotid plaque.

Variable Model 1 Model 2 Model 3
p HR (95%Cl) p HR (95%Cl) p HR (95%Cl)
High CHA2-DS2-VASC and Normal LAVI <0.0001 2.99 (1.64–5.43) 0.001 2.77 (1.50–5.12) 0.002 2.63 (1.41–4.89)
Low CHA2-DS2-VASC and Dilated LAVI 0.003 2.41 (1.35–4.29) 0.004 2.36 (1.33–4.21) 0.012 2.13 (1.18–3.85)
High CHA2-DS2-VASC and Dilated LAVI <0.0001 8.54 (5.14–14.19) <0.0001 7.74 (4.51–13.27) <0.0001 6.57 (3.70–11.65)
GFR (ml/m/m21.73) 0.291 0.99 (0.98–1.01) 0.384 0.99 (0.98–1.01)
LVH 0.106 1.39 (0.93–2.08)
Carotid Plaque 0.815 1.05 (0.71–1.54)

GFR = glomerular filtration rate; LAVI: left atrial volume index; LVH: left ventricular hypertrophy.