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. 2019 May 27;9:7866. doi: 10.1038/s41598-019-44256-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Levels of (a) IFN-γ, TNF-α, MCP-1, (b) IL-6, IL-8 and (c) NO released by M. tb H37Rv infected MDMs after treatment with Pep-H. Values are expressed as Mean ± SD of three independent experiments. The values of IFN-γ, TNF-α, MCP-1, IL-6, IL-8 obtained in control untreated infected MDMs are 0.15 ± 0.02, 41 ± 15.22, 2.05 ± 0.81, 231.53 ± 85.33, 40.23 ± 2.36 respectively as reported earlier¹⁸. For statistical analysis, one-way ANOVA was used and comparison was done with the levels of cytokines obtained in untreated infected MDMs. ***p < 0.001, **p < 0.01, w.r.t Control (Untreated infected MDMs).