Table 1.
Peptide fragments | Position | Antimicrobial Score | Charge | *Antimicrobial motif | |||
---|---|---|---|---|---|---|---|
AntiBP | AntiBP2 | CAMP | AMPA | ||||
ACYCRIPACIAGERR | 1–15 | 1.001 | −0.454 | 0.662 | — | +2 | Yes |
CYCRIPACIAGERRY | 2–16 | 1.120 | −0.702 | 0.816 | — | +2 | Yes |
YCRIPACIAGERRYG | 3–17 | −0.276 | −0.566 | 0.656 | — | +2 | NO |
CRIPACIAGERRYGT | 4–18 | 1.080 | −1.048 | 0.377 | — | +2 | NO |
RIPACIAGERRYGTC | 5–19 | 0.833 | −0.249 | 0.682 | — | +2 | Yes |
IPACIAGERRYGTCI | 6–20 | −1.425 | −0.629 | 0.296 | — | +1 | NO |
PACIAGERRYGTCIY | 7–21 | −0.261 | −0.996 | 0.505 | — | +1 | NO |
ACIAGERRYGTCIYQ | 8–22 | 0.829 | 0.637 | 0.519 | — | +1 | Yes |
CIAGERRYGTCIYQG | 9–23 | −0.515 | −0.051 | 0.450 | — | +1 | Yes |
IAGERRYGTCIYQGR | 10–24 | −0.368 | −0.242 | 0.357 | — | +2 | NO |
AGERRYGTCIYQGRL | 11–25 | 0.652 | 0.151 | 0.662 | — | +2 | Yes |
GERRYGTCIYQGRLW | 12–26 | −0.643 | −1.066 | 0.885 | — | +2 | NO |
ERRYGTCIYQGRLWA | 13–27 | −0.593 | −0.513 | 0.955 | — | +2 | NO |
RRYGTCIYQGRLWAF* | 14–28 | 0.806 | 0.089 | 0.946 | 0.218 | +3 | Yes |
RYGTCIYQGRLWAFC | 15–29 | −0.302 | −0.467 | 0.840 | — | +2 | NO |
YGTCIYQGRLWAFCC | 16–30 | −0.447 | −0.287 | 0.325 | — | +1 | NO |
The peptide highlighted in bold has antimicrobial potential based on antimicrobial score predictions by respective servers. *Antimicrobial motif: a short peptide having highest positive charge and predicted as antimicrobial based on scores obtained from all the servers. The motif RRYGTCIYQGRLWAF (highlighted in box) was selected as motif based on its antimicrobial score predictions.