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Determination of histone deacetylase (HDAC) activity upon treatment with three parthenolide concentrations. The known HDAC inhibitors vorinostat and trichostatin were used as control compounds at a concentration of each 10 μM. Asterisk (∗) indicates statistical significant inhibition (p < 0.05) while two asterisks (∗∗) indicate statistical significant (p < 0.01) compared to DMSO-treated control cells.
