Table 6. AUC of FF, R2*, and Combination of FF and R2* for Predicting Osteoporosis in Each Group.
| Parameters | Males (Age ≥ 50 Years) | Females (Postmenopausal) | ||||||
|---|---|---|---|---|---|---|---|---|
| Sensitivity (%) | Specificity (%) | AUC | P† | Sensitivity (%) | Specificity (%) | AUC | P† | |
| FF | ||||||||
| Reader 1 | 75.0 | 94.3 | 0.726 (0.592–0.836) | 0.326 | 40.0 | 100.0 | 0.689 (0.535–0.817) | 0.113 |
| Reader 2 | 75.0 | 98.1 | 0.762 (0.630–0.865) | 0.234 | 50.0 | 88.9 | 0.667 (0.512–0.799) | 0.158 |
| R2* | ||||||||
| Reader 1 | 100.0 | 35.8 | 0.651 (0.513–0.772) | 0.200 | 90.0 | 86.1 | 0.868 (0.736–0.950) | < 0.001 |
| Reader 2 | 100.0 | 47.2 | 0.698 (0.562–0.813) | 0.038 | 90.0 | 83.3 | 0.860 (0.726–0.944) | < 0.001 |
| FF + R2* | ||||||||
| Reader 1 | 75.0 | 92.5 | 0.717 (0.582–0.818) | 0.341 | 90.0 | 83.3 | 0.872 (0.741–0.952) | < 0.001 |
| Reader 2 | 75.0 | 96.2 | 0.778 (0.649–0.878) | 0.172 | 90.0 | 86.1 | 0.867 (0.734–0.949) | < 0.001 |
Younger males and premenopausal females included only one osteoporotic subject, resulting in insufficient data for ROC curve analysis. Numbers in parentheses are lower and upper bounds of 95% CIs. †p value of AUC.