Table 2.
Chromosome 17 abnormalities found by a conventional cytogenetic analysis at diagnosis in 548 patients with MDS treated with 5‐azacytidine
| Abnormality | Number of patients, N (%) | Comments |
|---|---|---|
| All chromosome 17 abnormalities | 32 (5.8) | |
| i(17)(q10) | 6 (18.8) | All cases as isolated chromosomal abnormalities |
| ‐17 | 15 (46.9) | All cases in the context of a complex karyotype; two cases with a concomitant translocation of chromosome 17; one case with add(17)(q23); one case with del(17)(q25) |
| add(17p11) | 3 | All cases in the context of a complex karyotype. |
| add(17p13) | 1 | |
| del(17)(q21) | 1 | |
| del(17)(p11.1) | 1 | |
| Translocation involving chromosome 17 | 6 | All except two cases in the context of a complex karyotype; two cases with concomitant ‐17 |
| dic(2‐17) | 1 | In the context of a complex karyotype |
add, addition; del, deletion; dic, dicentric; i, isochromosome.