Table 2.
Prediction for occurrence of prostate cancer
| Crude | P‐value | Adjusted | P‐value | |
|---|---|---|---|---|
| cHR | aHR | |||
| Metformin vs Nonmetformin | 0.65 (0.45‐0.93) | 0.0195 | 0.69 (0.49‐0.96) | 0.0298 |
| Severity of type 2 diabetes | ||||
| Low | Ref. | Ref. | ||
| Midden | 0.77 (0.42‐1.42) | 0.4004 | 0.89 (0.58‐1.37) | 0.6033 |
| High | 1.09 (0.51‐2.35) | 0.8217 | 1.27 (0.82‐1.97) | 0.2938 |
| TCM for DM | 0.27 (0.14‐0.52) | 0.0001 | 1.04 (0.62‐1.74) | 0.8817 |
| TCM for BPH | 0.17 (0.08‐0.37) | <0.0001 | 0.41 (0.24‐0.69) | 0.0009 |
| Insulin usage | 0.29 (0.09‐0.87) | 0.0271 | 0.53 (0.25‐1.10) | 0.0891 |
| Comorbidities | ||||
| Myocardial infarction | NA | NA | ||
| Congestive heart failure | 0.33 (0.07‐1.65) | 0.1785 | 0.51 (0.12‐2.09) | 0.3514 |
| Peripheral vascular disease | 1.50 (0.61‐3.67) | 0.3744 | 1.62 (0.40‐6.59) | 0.5012 |
| Cerebrovascular disease | NA | 1.17 (0.75‐1.84) | 0.4890 | |
| Dementia | 1.50 (0.42‐5.32) | 0.5299 | NA | |
| Chronic lung disease | NA | 0.79 (0.38‐1.62) | 0.5190 | |
| Connective tissue disease | 1.33 (0.46‐3.84) | 0.5943 | NA | |
| Ulcer | 2.00 (0.60‐6.64) | 0.2577 | 1.76 (1.26‐2.45) | 0.0009 |
| Chronic liver disease | 0.50 (0.09‐2.73) | 0.4236 | 1.31 (0.88‐1.95) | 0.1880 |
| Hemiplegia | NA | 0.82 (0.19‐3.49) | 0.7845 | |
| Moderate or severe kidney disease | 1.00 (0.14‐7.10) | >0.9999 | NA | |
| Tumor, leukemia, lymphoma | NA | 2.10 (1.02‐4.30) | 0.0435 | |
| Moderate or severe liver disease | NA | NA | ||
| Malignant tumor, metastasis | NA | NA | ||
| AIDS | NA | NA | ||
| Retinopathy | NA | 0.84 (0.20‐3.43) | 0.8055 | |
| Nephropathy | 0.50 (0.09‐2.73) | 0.4236 | 5.39 (2.29‐12.68) | 0.0001 |
| Neuropathy | 0.65 (0.45‐0.93) | 0.0195 | 0.54 (0.13‐2.22) | 0.3968 |
| Erectile dysfunction | 0.98 (0.54‐1.76) | 0.9395 | 0.95 (0.52‐1.72) | 0.8642 |
AIDS, acquired immune deficiency syndrome; BPH, benign prostate hyperplasia; DM, diabetes mellitus; TCM, traditional Chinese medicine.