Table 2.

Cross-sectional associations of liver fat and liver enzymes with free and protein-bound AGEs and sRAGE.

Outcome	Model	eLF% (%)				Liver enzyme score
		β	95% CI		P value	β	95% CI		P value
Free CML (nM)	1	0.042	0.002	0.082	0.038	0.030	0.000	0.060	0.052
	2	0.031	-0.008	0.070	0.122	0.030	-0.001	0.061	0.055
	3	0.041	-0.002	0.084	0.061	0.046	0.015	0.077	0.004
	4	0.037	-0.014	0.088	0.151	0.044	0.012	0.076	0.008
Free CEL (nM)	1	0.096	0.058	0.135	<0.001	0.047	0.018	0.077	0.002
	2	0.083	0.045	0.121	<0.001	0.037	0.007	0.067	0.016
	3	0.095	0.054	0.136	<0.001	0.049	0.019	0.079	0.001
	4	0.090	0.041	0.139	<0.001	0.040	0.009	0.072	0.012
Free MG-H1 (nM)	1	0.043	-0.019	0.105	0.170	-0.009	-0.056	0.038	0.719
	2	0.023	-0.038	0.084	0.464	-0.019	-0.067	0.028	0.423
	3	0.024	-0.042	0.090	0.481	0.006	-0.042	0.053	0.820
	4	0.036	-0.042	0.115	0.367	0.007	-0.043	0.057	0.789
PB-pentosidine (nmol/mmol lysine)	1	-0.059	-0.100	-0.018	0.005	-0.015	-0.047	0.016	0.342
	2	-0.076	-0.117	-0.035	<0.001	-0.028	-0.060	0.004	0.088
	3	-0.102	-0.146	-0.058	<0.001	-0.032	-0.064	0.001	0.055
	4	-0.051	-0.102	0.001	0.055	-0.007	-0.040	0.026	0.676
PB-CML (nmol/mmol lysine)	1	-0.115	-0.143	-0.087	<0.001	-0.061	-0.083	-0.039	<0.001
	2	-0.122	-0.150	-0.093	<0.001	-0.067	-0.090	-0.044	<0.001
	3	-0.105	-0.136	-0.074	<0.001	-0.054	-0.077	-0.031	<0.001
	4	-0.071	-0.108	-0.034	<0.001	-0.037	-0.060	-0.013	0.002
PB-CEL (nmol/mmol lysine)	1	0.000	-0.036	0.036	0.992	0.003	-0.025	0.031	0.828
	2	-0.002	-0.039	0.035	0.911	-0.002	-0.030	0.027	0.919
	3	0.013	-0.028	0.055	0.527	0.007	-0.023	0.037	0.652
	4	-0.003	-0.052	0.047	0.920	0.001	-0.030	0.033	0.939
sRAGE (pg/ml)	1	-0.097	-0.146	-0.048	<0.001	-0.072	-0.109	-0.034	<0.001
	2	-0.076	-0.125	-0.028	0.002	-0.040	-0.078	-0.002	0.039
	3	-0.076	-0.130	-0.023	0.005	-0.027	-0.067	0.012	0.169
	4	-0.039	-0.102	0.025	0.232	-0.010	-0.050	0.031	0.642

β-Values are unstandardized regression coefficients and represent the change in AGEs and sRAGE (all ln-transformed) per one unit increase in eLF% (ln-transformed) or the LE score. Model 1: crude model. Model 2: model 1 + adjustment for age and sex. Model 3: model 2 + adjustment for alcohol, smoking, CVD, medication, and eGFR. Model 4: model 3 + adjustment for BMI. 95% CI: 95% confidence interval.