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. 2019 May 15;5(2):2055217319848463. doi: 10.1177/2055217319848463

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© The Author(s) 2019

Creative Commons CC-BY: This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Scatter dot plots of cytokines and chemokines in cerebrospinal fluid (CSF) and serum of the validation set. Individual values for aquaporin-4-antibody (AQP4-Ab), myelin oligodendrocyte glycoprotein-antibody (MOG-Ab), anti-N-methyl-D-aspartate receptor-antibody (NMDAR-Ab) and multiple sclerosis (MS) patients are shown as circles and medians are shown as bars. Cytokines and chemokines are organised according to their p-values. Overall significance was assessed using the nonparametric Kruskal Wallis test and p-values were adjusted for multiple comparisons using a false discovery rate (FDR) significance criterion of 10% based on the Benjamini-Hochberg correction. Between group comparisons were calculated using Dunn’s multiple comparison test. Significant changes in the CSF (AQP4-Ab and MOG-Ab versus MS) and serum (AQP4-Ab, MOG-Ab and NMDAR-Ab versus MS) are shown in the graphs.Ab: antibody; AQP-4: aquaporin-4; GRO: growth-regulated oncogene; IL: interleukin; IP: interferon-ɣ-induced protein; MCP: monocyte chemoattractant protein; MIG: monokine induced by interferon-ɣ; MIP: macrophage inflammatory protein; MOG: myelin oligodendrocyte glycoprotein; MS: multiple sclerosis; NMDAR: N-methyl-D-aspartate receptor; ns: not significant.