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95% bootstrapped confidence interval of causal estimates (log odds) of CSF‐A β 1–42 protein levels on AD progression using CIV_smooth and Allele methods in external validation sample set‐ups. It is important to note that the confidence interval shown here for sisVIVE methods results from treating Y as continuous, since sisVIVE is not designed for binary outcomes. These results show a decrease in AD risk with higher amyloid beta levels.
