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. 2019 May 27;19:498. doi: 10.1186/s12885-019-5732-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — A patient with rectal adenocarcinoma (pT4N1, moderately differentiated). a Sagittal high-resolution T2WI depicted definitive tumour signal within a marked expanded and irregular extramural vessel (arrow), confirming mrEMVI-positive status. c A VOI (pink dashed line) was selected on DCE-MRI, and (d) the AIF with the smallest chi-square value was the selected. c An ROI (red continuous line) was drawn along the edge of the tumour guided by corresponding (b) oblique axial high-resolution T2WI. e The ROI was copied to K^trans map, and the mean K^trans (0.121 min^− 1), k_ep (0.514 min^− 1) and v_e (0.258) values were obtained