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. 2019 Apr 8;24(5):537–547. doi: 10.1177/2472555219838341

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© 2019 Society for Laboratory Automation and Screening

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — Concordance testing of IC50 values for anti-Wolbachia activity and host cell toxicity across a set of 20 compounds from the A∙WOL drug discovery program. (A) Anti-Wolbachia IC50 values in A·WOL legacy screens versus acumen screen at AstraZeneca. (B) Toxicity IC50 values in legacy versus EnVision screen at AstraZeneca. (C) acumen anti-Wolbachia IC50 values for occasion 1 versus occasion 2 in the AstraZeneca screen. (D) EnVision toxicity IC50 values for occasion 1 versus occasion 2 in the AstraZeneca screen.