Fig. 3.

Solid tumor (non-CNS) oncoprint of most common Tier 1 and 2 SNVs, idels, and fusions. Summary of most commonly encountered Tier 1 or 2 SNVs and fusion variants identified in > 1 solid tumor. TP53 was the most commonly encountered SNV, followed by KRAS, ALK, and BRCA2. EWSR1-FLI1 was the most common fusion gene, followed by FOXO1 fusions, present in a total of four tumors. Overall number of clinically significant variants per tumor is represented across the top, with eight tumors have > 1 alteration. The number of variants identified per gene is represented to the right. Age and tumor type are represented across the bottom. CNS = central nervous system, SNV = single nucleotide variant, indel = insertion/deletion