Fig. 6.

Clinical impact of panel sequencing. Cases were considered positive for clinical impact (+) if they contained clinically significant Tier 1 or 2 variants. a. Overall, 289 cases (78.7%) had positive clinical impact for at least one type of category (diagnostic, prognostic, therapeutic, potential germline). The bar chart on the right shows the percentage of cases with clinically significant Tier 1 or 2 variants impacting each category. b. Summary of clinical impact color-coded by tumor type and impact category. Pie chart depicts number of patients in each slice. Hash marks indicate no clinical impact while solid color indicate positive clinical impact