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. 2019 May 28;20:266. doi: 10.1186/s12859-019-2889-z

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© The Author(s) 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Results of four selection methods used in CODEX, CNVkit and exomeCopy. Panels a, c, e present absolute changes in the precision and sensitivity of the investigated CNV callers for different methods of the reference set selection; relative performance in relation to baseline is presented in panels b, d, and f. The results for the “all” method (baseline) are presented in the “kmeans” diagram, where k is equal to 1 (single group)