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. 2019 May 27;10:149. doi: 10.1186/s13287-019-1260-7

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — HNF-4α-MSCs inhibited Kupffer cell-associated inflammation. a Concentrations of the inflammatory factors TNF-α, IFN-γ and IL-6 were detected in mouse serum on the sixth week using a Bio-plex assay. b Expression of ALB was detected using IHC (× 320). c The Kupffer cell marker CD68 was detected in mouse livers using IHC (× 200). d Quantification of panel c. Three fields of view were selected for each group to count the CD68-positive cells. The mean of the three fields was used to represent the CD68⁺ cells for each group. (Five mice were used in each group. The data are represented as the mean ± S.D.) Scale bars, 100 μm