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. 2019 May 28;38:224. doi: 10.1186/s13046-019-1229-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — The leukemogenic capacity of bcr-abl in mice was impaired by RFNs. a WBC counts in each group were counted. The maximum value of each mouse was recorded. b, c The weights of spleen and liver of mice in each group were measured. d The amount of human CD45⁺ cells was tested by flow cytometry. e The expression of BCR-ABL protein in each group was detected by immunofluorescent assay. f Immature cells from bone marrow were checked by Wright’s stain and the infiltration of spleen and liver was analyzed by H&E stain. g Kaplan-Meier method to analyze the survival curves of mice in each group