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. 2019 May 27;19:111. doi: 10.1186/s12866-019-1466-y

Table 5.

Differences in stool microbiota taxon between different groups of glucose levels

Overall comparison
 Taxon

GLU normal

(Mean ± SD)

GLU high

(Mean ± SD)

 Wilcoxon rank-sum test Discriminatory power

GLU normal

(Mean ± SD)

DM

(Mean ± SD)

 Wilcoxon rank-sum test Discriminatory power
p-value q-value AUC value sig. p-value q-value AUC value sig.
 p__Actinobacteria 0.0253 ± 0.0363 0.0761 ± 0.0921 0.0003 0.018 0.6848 0.0004 0.0253 ± 0.0363 0.0846 ± 0.088 0 0.0028 0.7463 0.0003
 p__Actinobacteria.c__Actinobacteria 0.0253 ± 0.0363 0.0761 ± 0.0921 0.0003 0.018 0.6848 0.0004 0.0253 ± 0.0363 0.0846 ± 0.088 0 0.0028 0.7463 0.0003
 p__Actinobacteria.c__Actinobacteria.o__Bifidobacteriales 0.0161 ± 0.026 0.0631 ± 0.0815 0.0001 0.0099 0.6976 0.0003 0.0161 ± 0.026 0.0714 ± 0.0855 0 0.0028 0.7475 0.0004
 p__Actinobacteria.c__Actinobacteria.o__Bifidobacteriales.f__Bifidobacteriaceae 0.0161 ± 0.026 0.0631 ± 0.0815 0.0001 0.0099 0.6976 0.0003 0.0161 ± 0.026 0.0714 ± 0.0855 0 0.0028 0.7475 0.0004
 p__Actinobacteria.c__Actinobacteria.o__Bifidobacteriales.f__Bifidobacteriaceae.g__Bifidobacterium 0.0161 ± 0.026 0.062 ± 0.0803 0.0001 0.0099 0.6969 0.0003 0.0161 ± 0.026 0.0696 ± 0.084 0 0.0028 0.7457 0.0004
 p__Firmicutes.c__Bacilli 0.0033 ± 0.0069 0.0357 ± 0.0942 0.0008 0.042 0.6714 0.0021 0.0033 ± 0.0069 0.0315 ± 0.0799 0.001 0.0476 0.6981 0.0028
 p__Firmicutes.c__Bacilli.o__Lactobacillales 0.0032 ± 0.0069 0.0353 ± 0.0923 0.0009 0.0444 0.669 0.0021 0.0032 ± 0.0069 0.0315 ± 0.0799 0.001 0.0476 0.6985 0.0027
 p__Firmicutes.c__Bacilli.o__Lactobacillales.f__Lactobacillaceae 0.0011 ± 0.0053 0.0271 ± 0.0812 0 0.0099 0.7064 0.0155 0.0011 ± 0.0053 0.0238 ± 0.0752 0 0.0028 0.7479 0.0268
 p__Firmicutes.c__Bacilli.o__Lactobacillales.f__Lactobacillaceae.g__Lactobacillus 0.0011 ± 0.0053 0.0271 ± 0.0812 0 0.0099 0.7064 0.0155 0.0011 ± 0.0053 0.0238 ± 0.0752 0 0.0028 0.7479 0.0268
Comparison among 76 ages and older subgroup
 Taxon

GLU normal

(Mean ± SD)

GLU high

(Mean ± SD)

 Wilcoxon rank-sum test Discriminatory power

GLU normal

(Mean ± SD)

DM

(Mean ± SD)

 Wilcoxon rank-sum test Discriminatory power
p-value q-value AUC value sig. p-value q-value AUC value sig.
 p__Actinobacteria 0.0293 ± 0.0363 0.1322 ± 0.0917 0 0.0004 0.8725 0.0011 0.0293 ± 0.0363 0.1581 ± 0.0934 0 0.0002 0.926 0.0017
 p__Actinobacteria.c__Actinobacteria 0.0293 ± 0.0363 0.1322 ± 0.0917 0 0.0004 0.8725 0.0011 0.0293 ± 0.0363 0.1581 ± 0.0934 0 0.0002 0.926 0.0017
 p__Actinobacteria.c__Actinobacteria.o__Bifidobacteriales 0.0231 ± 0.0348 0.1169 ± 0.0907 0 0.0004 0.8725 0.0015 0.0231 ± 0.0348 0.1384 ± 0.0959 0 0.0002 0.9201 0.0023
 p__Actinobacteria.c__Actinobacteria.o__Bifidobacteriales.f__Bifidobacteriaceae 0.0231 ± 0.0348 0.1169 ± 0.0907 0 0.0004 0.8725 0.0015 0.0231 ± 0.0348 0.1384 ± 0.0959 0 0.0002 0.9201 0.0023
 p__Actinobacteria.c__Actinobacteria.o__Bifidobacteriales.f__Bifidobacteriaceae.g__Bifidobacterium 0.0231 ± 0.0348 0.1164 ± 0.09 0 0.0004 0.8745 0.0015 0.0231 ± 0.0348 0.1378 ± 0.0951 0 0.0002 0.9201 0.0022
 p__Bacteroidetes.c__Bacteroidia.o__Bacteroidales.f__Bacteroidaceae 0.29 ± 0.1638 0.1333 ± 0.1286 0.0015 0.0464 0.7733 0.0052 0.29 ± 0.1638 0.1249 ± 0.1186 0.0028 0.0867 0.7899 0.0094
 p__Bacteroidetes.c__Bacteroidia.o__Bacteroidales.f__Bacteroidaceae.g__Bacteroides 0.29 ± 0.1638 0.1333 ± 0.1286 0.0015 0.0464 0.7733 0.0052 0.29 ± 0.1638 0.1249 ± 0.1186 0.0028 0.0867 0.7899 0.0094
 p__Firmicutes.c__Bacilli 0.0032 ± 0.0053 0.0822 ± 0.1438 0.0001 0.0042 0.834 0.0047 0.0032 ± 0.0053 0.068 ± 0.1172 0.0002 0.0091 0.8491 0.0048
 p__Firmicutes.c__Bacilli.o__Lactobacillales 0.0032 ± 0.0053 0.0811 ± 0.1406 0.0001 0.0042 0.832 0.0047 0.0032 ± 0.0053 0.0679 ± 0.1171 0.0002 0.0091 0.8491 0.0048
 p__Firmicutes.c__Bacilli.o__Lactobacillales.f__Lactobacillaceae 0.0012 ± 0.0037 0.0647 ± 0.1244 0 0.0001 0.9069 0.0259 0.0012 ± 0.0037 0.0574 ± 0.1116 0 0.0002 0.9201 0.0262
 p__Firmicutes.c__Bacilli.o__Lactobacillales.f__Lactobacillaceae.g__Lactobacillus 0.0012 ± 0.0037 0.0647 ± 0.1244 0 0.0001 0.9069 0.0259 0.0012 ± 0.0037 0.0574 ± 0.1116 0 0.0002 0.9201 0.0262
 p__Firmicutes.c__Clostridia.o__Clostridiales.f__Lachnospiraceae 0.233 ± 0.12 0.1087 ± 0.0799 0.0003 0.0153 0.8057 0.0031 0.233 ± 0.12 0.0925 ± 0.0574 0.0002 0.0091 0.855 0.0048
 p__Firmicutes.c__Clostridia.o__Clostridiales.f__Lachnospiraceae.g__Lachnospiracea_incertae_sedis 0.0305 ± 0.026 0.0107 ± 0.0099 0.0014 0.0464 0.7753 0.0147 0.0305 ± 0.026 0.01 ± 0.0094 0.0028 0.0867 0.7899 0.0303