Table 1.
Baseline characteristics of all randomised children stratified by treatment arm. Data are n (%), median (IQR), mean (SD). BMI = body-mass index, EPG = eggs per gram of stool.
| Single dose (n = 93) | Multiple dose (n = 93) | |
|---|---|---|
| Mean age (years) | 10.1 (1.6) | 10.1 (1.6) |
| Girls | 39 (42%) | 46 (50%) |
| Mean weight (kg) | 26.7 (5.3) | 26.2 (5.1) |
| Mean height (cm) | 132.0 (10.2) | 131.8 (9.6) |
| Mean weight-for-age Z-score | − 1.4 (1.2) | − 1.3 (0.8) |
| Mean height-for-age Z-score | − 1.1 (1.1) | − 1.1 (0.7) |
| Mean BMI-for-age Z-score | − 1.1 (0.9) | − 1.2 (0.8) |
| Hookworm | ||
| Infected children | 93 (100%) | 93 (100%) |
| Median | 222 (78-534) | 222 (96-606) |
| EPG geometric mean | 219.0 | 234.2 |
| Infection intensity | ||
| Light (1–1999 EPG) | 89 (96%) | 90 (97%) |
| Moderate (2000–3999 EPG) | 3 (3%) | 3 (3%) |
| Heavy (≥ 4000 EPG) | 1 (2%) | 0 |
| Trichuris trichiura | ||
| Infected children | 88 (96%) | 91 (98%) |
| EPG geometric mean | 661.8 | 725.7 |
| Infection intensity | ||
| Light (1–999 EPG) | 59 (66%) | 56 (62%) |
| Moderate (1000–9999 EPG) | 30 (34%) | 35 (38%) |
| Heavy (≥ 10,000 EPG) | 0 | 0 |
| Ascaris lumbricoides | ||
| Infected children | 47 (51%) | 51 (55%) |
| EPG geometric mean | 2691.2 | 4095.9 |
| Infection intensity | ||
| Light (1–4999 EPG) | 28 (60%) | 20 (39%) |
| Moderate (5000–49,999 EPG) | 15 (32%) | 28 (55%) |
| Heavy (≥ 50,000 EPG) | 4 (8%) | 3 (6%) |