Table 3.
Incidence of long-term renal events in the standard prophylactic treatment (H +) and no prophylactic treatment (H −) groups.
| H + groupa n (%) |
H − groupa n (%) |
Absolute difference H − in H + |
95% confidence interval | p value | |
|---|---|---|---|---|---|
| Renal failure (eGFR < 15 mL/min/1.73 m2) | 0/297 (0.00) | 1/292 (0.34) | + 0.34 | − 0.97 to 1.91 | 0.3150 |
| > 10 eGFR unit renal function decline with from baseline | 28/297 (9.43) | 28/292 (9.59) | + 0.16 | − 4.65 to 4.99 | 0.9473 |
| Renal function decline to eGFR < 30 mL/min/1.73 m2 | 9/297 (3.03) | 8/292 (2.74) | − 0.29 | − 2.65 to 3.24 | 0.8337 |
| Both > 10 eGFR unit decline from baseline and a decline to eGFR < 30 mL/min/1.73 m2 | 11/297 (3.70) | 10/292 (3.42) | + 0.28 | − 2.92 to 3.49 | 0.8547 |
eGFR = estimated glomerular filtration rate.
a
Long-term serum creatinine data were available for 589/660 (89%) patients: for 297/328 (91%) of the H + group and for 292/332 (88%) of the H − group.