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. 2018 Aug 9;84(6):1214–1224. doi: 10.1093/neuros/nyy365

TABLE 1.

Clinical Characteristics

ALA
All (n = 74) No fluorescence (n = 58) Fluorescence (n = 16)
Variable Avg SD M n n/N Avg SD M n n/N Avg SD M n n/N P a
Age 42.8 13.4 41.0 42.8 13.1 41.0 43.0 14.7 41.1 .956
Gender male 42 56.8% 35 60.3% 7 43.8% .236
female 32 43.2% 23 39.7% 9 56.3%
KPS 80 4 5.4% 3 5.2% 1 6.3% .030
90 12 16.2% 6 10.3% 6 37.5%
100 58 78.4% 49 84.5% 9 56.3%
Volume ccm 11.4 20.1 6.00 13.0 22.5 6.00 5.79 3.16 6.0 .207
Enhancement no 56 75.7% 49 84.5% 7 43.8% .001
(weak, indistinct) yes 18 24.3% 9 15.5% 9 56.3%
FETmaxb 2.45 1.29 2.35 2.24 1.29 2 3.21 0.952 3 .009
EoR >90% 24 32.4% 21 36.2% 3 18.8% .187
<90% 50 67.6% 37 63.8% 13 81.3%
Volume ccm 11.4 20.1 6.00 13.0 22.5 6.00 5.79 3.16 6.0 .207
Adj. none 39 52.7% 32 55.2% 7 43.8% .335
Cytotoxic chemo 9 12.2% 8 13.8% 1 6.3%
Therapy RT 24 32.4% 16 27.6% 8 50.0%
missing 2 2.7% 2 3.4% 0 0.0%

aChi2 for categories and ANOVA for continuous data; avg, average; SD, standard deviation; M, median; EoR, extent of resection; KPS, Karnofsky Performance Score; ccm, cubic centimeters; FETmax, maxium standard uptake ratio; RT, radiotherapy; chemo, chemotherapy; bn = 70 patients; non-fluorescing tumors: 55, fluorescing tumors 15.