Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 May 21;10:555. doi: 10.3389/fphar.2019.00555

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Mango and Nisticò.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

PcTx-1 inhibits chemical NMDA-LTD. (A) Pooled data showing LTD induced by NMDA (20 μM) bath applied in slices obtained from young mice in control condition (n = 9) (black), in the presence of PcTx-1 (n = 7) (100 ng/ml, pink) applied before and during NMDA application, or applied after LTD induction (n = 6) (grey). Histogram represents the last 5 min of experiment in each condition (mean ± SEM, ***p < 0.001). On the top, representative traces are shown for each condition. (B) Pooled data showing LTD induced by NMDA (20 μM) bath applied in slices obtained from adult mice in control condition (n = 8) (black), in the presence of PcTx-1 (n = 7) (100 ng/ml, pink) applied before and during NMDA application, or applied after LTD induction (n = 5) (grey). Histogram represents the last 5 min of experiment in each condition (mean ± SEM, ***p < 0.001). On the top, representative traces are shown for each condition.