Skip to main content
. 2019 May 19;25:3700–3715. doi: 10.12659/MSM.914162

Figure 1.

Figure 1

The transcriptional level of FTH1 gene is higher in renal cell carcinoma (RCC) than in normal kidney tissues. (A) The mRNA expression of FTH1 in 890 cases of RCC and 129 cases of normal kidney tissues based on TCGA database. (B) FTH1 mRNA expression was detected by RT-qPCR in renal cancer cell 786-0 and renal epithelial cell 293, normalized to GAPDH. (C) The mRNA expression of FTH1 in 14 primary renal cell carcinoma tissues and matched adjacent tissues. (D) The ROC curve for evaluating the diagnostic performance of FTH1 in 890 cases of RCC and 129 cases of normal kidney tissues. The AUC was 0.849. (E) The overall survival (OS) of RCC patients with high and low mRNA level of FTH1, which was divided by the median of FTH1 mRNA expression in 890 cases of RCC.