Table 3.
Our study (2016) | Krishna et al.[7] (2015) | Gohel et al.[6] (2014) | Padmavathi et al.[22] (2013) | Anjaneyan et al.[18] (2013) | |
---|---|---|---|---|---|
Type of CADRS | 1. Rash | 1. Fixed drug eruptions | 1. Rash | 1. Fixed drug eruption | 1. Itching |
2. Itching or burning | 2. Acne | 2. Pruritus | 2. Maculopapular rash | 2. Rash | |
3. SJ syndrome | 3. Urticaria | 3. Urticaria | 3. Urticaria | 3. Swelling | |
Causal drug groups | 1. Antimicrobials | Not done | 1. Antimicrobials | 1. Antimicrobials | 1.Antimicrobials |
2. NSAIDs | 2. NSAIDs | 2. NSAIDs | 2. NSAIDs | ||
3. Antiepileptic | 3. Not mentioned | 3. Unknown | 3. Antiepileptic | ||
Causality | |||||
1. WHO-UMC | Not done | 21% | |||
‑Possible | 65.56% | 17.4% | 54.64% | 70% | |
‑ Probable | 32.99% | 52.4% | 36.08% | ||
2. Naranjo’s score | |||||
‑Possible | 54.61% | Not done | 21.65% | 22% | Not done |
‑Probable | 45.38% | 74.23% | 78% | ||
Severity | |||||
‑Mild | 18.58% | 30.4% | 2% | 41.5% | Not done |
‑Moderate | 81.2% | 65.3% | 98% | 58.5% | |
‑Severe | 0.18% | 4.3% | 0 | 0 | |
Preventability | |||||
Definitely | – | 43.5% | 72.15% | 12.2% | Not done |
Probably | 11.10% | 30.4% | 27.84% | – | |
Not preventable | 88.90% | 26.1% | – | 87.8% |