Table 2. Estimation of year of MRCA of EV-A71 subgenogroup C1v2015 lineage by using different enteroviruses*.

Node†	Year of MRCA (95% HPD interval)
	Genomic region P1	3Dpol gene
1‡	2013.6 (2013.2–2014.1)	2013.6 (2012.9–2014.3)
2§	2010.2 (2009–2011.3)	2004.1 (2001.7–2006.2)
3¶	2000.5 (2000.1–2001.6)	ND
Root	1986 (1984.7–1987.3)	ND

*EV-A71, enterovirus A71; HPD, highest probability density; MRCA, most recent common ancestor; ND, not done.
†MRCAs were determined for nodes and root in Figure 2.
‡Node 1 represents the MRCA of all included EV-A71 C1v2015 isolates except the virus from patient 14.
§For genomic region P1, node 2 represents the MRCA of all EV-A71 C1v2015 isolates, including the virus from patient 14. For 3Dpol gene, node 2 represents the MRCA of EV-A71 C1v2015 and its parent C1 lineage.
¶Node 3 represents the MRCA of EV-A71 C1v2015 and its parent C1 lineage.