Figure 2.

Phylogenomic relationship of 105 Bordetella pertussis epidemic isolates from Australia. The minimum-evolution tree was constructed using 705 SNPs. The isolates are labeled by name (L numbers), followed by states with color to indicate years of isolates. Shaded areas inside circle indicate ELs (EL1–EL5) and branches with isolates belonging to SP18 and those carrying fim3B and prn3 alleles. Prn-positive isolates and different mechanisms of Prn-negative isolates are marked by circles with different colors. Scale bar represents 3 SNPs. EL, epidemic lineage; NSW, New South Wales; Prn, pertactin; SNP, single-nucleotide polymorphism; SP, SNP profile; WA, Western Australia.