Table. Mechanisms of pertactin deficiency and characteristics of Bordetella pertussis isolates from pertussis epidemics, Australia, 2013–2017*.

Prn deficiency mechanism	Position in prn†	prn allele type	State (no. of isolates)	Year (no. isolates)	References
IS481F	1613	prn2	Western Australia (32)	2013 (13)	(1)
			New South Wales (10)	2014 (5)
				2015 (11)
				2016 (9)
				2017 (4)
IS481R	1613	prn2	Western Australia (12)	2013 (6)	(1)
			New South Wales (5)	2014 (5)
				2015 (4)
IS481F	1598	prn3	Western Australia (3)	2013 (1)	This study
				2014 (2)
IS1002R	1613	prn2	Western Australia (4)	2013 (2)	(1)
				2016 (1)
				2017 (1)
Deletion	−297 to 1325	Not determined‡	Western Australia (2)	2014 (1)	(8), newly found in Australia
				2015 (1)
Stop codon	223	prn2	Western Australia (1)	2014 (1)	(10), newly found in Australia
Deletion	2020–2023	prn2	Western Australia (1)	2013 (1)	This study

*F/R denotes IS insertion orientation relative to prn. F, forward; IS, insertion sequence; Prn, pertactin; R, reverse.
†The nucleotide positions are relative to the initiation codon (ATG) of the prn in Tohama I.
‡prn allele type was not determinable because the repeat regions that define prn allele type was deleted in this mechanism.