Table 3. Multivariate Analysis of the Predictors for ISS>15 in the Central Netherlands Regiona.
| Variables | β Coefficient (SD) | P Value | OR (95% CI) |
|---|---|---|---|
| Patient characteristics | |||
| Age, y | |||
| Spline basis function 1 | 0.011 (0.004) | .001 | 3.24 (−0.003 to 0.026) |
| Spline basis function 2 | 0.001 (0.005) | .86 | 0.18 (−0.018 to 0.018) |
| Physiologic characteristics | |||
| Systolic blood pressure | |||
| Spline basis function 1 | −0.011 (0.002) | <.001 | −4.97 (−0.018 to 0.003) |
| Spline basis function 2 | 0.020 (0.003) | <.001 | 7.14 (0.007 to 0.031) |
| GCS score | −0.337 (0.001) | <.001 | −36.69 (−0.391 to −0.291) |
| Mechanism of injury | |||
| Mechanism criteriab | 1.314 (0.056) | <.001 | 23.40 (1.060 to 1.547) |
| Injury characteristics | |||
| Penetrating injury to head, thorax, or abdomen | 1.196 (0.131) | <.001 | 9.13 (0.555 to 1.755) |
| Signs and/or symptoms of head or neck injury | 0.571 (0.056) | <.001 | 10.23 (1.318 to 0.829) |
| Expected injury in AIS region of thorax | 0.405 (0.071) | <.001 | 5.72 (0.079 to 0.742) |
| Expected injury in ≥2 AIS regions | 0.713 (0.129) | <.001 | 12.79 (0.440 to 0.988) |
| Interceptc | 2.069 (0.315) | <.001 | 6.57 (0.541 to 3.324) |
Abbreviations: AIS, Abbreviated Injury Scale; GCS, Glasgow Coma Scale; ISS, Injury Severity Score.
a
Includes 4950 patients in the design data cohort. Multiple imputation was used to account for the missing prehospital variables, including oxygen saturation level in 662 (13.4%) and GCS in 230 (4.6%).
b
Include fall of greater than 2 m, motorcycle crash of greater than 32 km/h, or entrapment of a person or body part.
c
Intercept is 0.894 for the Brabant region.