Table 3. Comparative Effectiveness of Pulmonary Artery Pressure Sensor-Based Management on Clinical Event Rates and Days Lost.
Outcome | Mean (SD) | Hazard Ratioa or Risk Ratiob (95% CI) | Absolute Difference, d | P Value | |
---|---|---|---|---|---|
Treatment Cohort (n = 1087) | Control Cohort (n = 1087) | ||||
Clinical event rates per patient per y | |||||
Heart failure hospitalizationc | 0.65 | 0.88 | 0.76 (0.65-0.89) | NA | <.001 |
Mortality, death per y | 0.23 | 0.30 | 0.70 (0.59-0.83) | NA | <.001 |
Heart failure or death | 0.90 | 1.23 | 0.73 (0.64-0.84) | NA | <.001 |
Days lost per patienta | |||||
To death | 46.2 | 64.2 | 0.72 (0.62-0.84) | −17.9 | <.001 |
To heart failure hospitalization or death | 50.0 | 68.4 | 0.73 (0.63-0.85) | −18.5 | <.001 |
To any-cause hospitalization or death | 56.9 | 74.5 | 0.77 (0.68-0.88) | −17.5 | <.001 |
Abbreviation: NA, not applicable.
Hazard ratios, 95% CIs, and P values for events were derived using the Andersen-Gill extension of the Cox proportional hazards model. Mortality rates are the Kaplan-Meier estimates of mortality.
Mean, 95% CI, hazard ratio, and P values for comparing days lost were derived from nonparametric bootstrap model.
Inpatient heart failure hospitalization; identified in primary diagnosis code per Centers for Medicare and Medicaid Services.