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Comparison of the AAV Particle Types Determined by Electron Microscopy with Manual Image Counting (EM) and Charge Detection Mass Spectrometry (CDMS)a
| full | ambiguous/partial | empty | |
|---|---|---|---|
| EM | 0.43 (±0.16) | 0.27 (±0.15) | 0.30 (±0.16) |
| CDMS | 0.421 (±0.004) | 0.288 (±0.006) | 0.291 (±0.002) |
The numbers indicate the fractions of the different particle types in the 1:15 v/v mixed sample (see text). Numbers in parentheses are standard deviations for multiple analyses of the same data set.
