Table 3.
Patient- and HCP-assessed symptoms that need to be addressed by treatment and those that are not adequately treated.
| Domain | Phase | Symptoms most needed to be addressed by treatment | Symptoms not adequately treated | ||
|---|---|---|---|---|---|
| aPatient cohort, % | bHCP-assessed cohort, % | cPatient cohort, % | dHCP-assessed cohort, % | ||
| Mood | Acute | 92* | 88 | 75** | 47 |
| Post-acute | 91** | 75 | 69** | 51 | |
| Remission | 83** | 64 | 60** | 43 | |
| Physical | Acute | 84** | 64 | 72** | 36 |
| Post-acute | 79** | 58 | 66** | 39 | |
| Remission | 74** | 62 | 65** | 40 | |
| Cognitive | Acute | 71** | 39 | 55** | 33 |
| Post-acute | 58** | 47 | 49** | 32 | |
| Remission | 56 | 49 | 40 | 40 | |
Data are percentage of patients.
Q19 (Patient) What are the symptoms that you most want your treatment to address? Baseline: Patients who experience each group of symptoms. Baseline: patients, mood: acute, n = 408; post-acute, n = 761; remission, n = 635/physical: acute, n = 407; post-acute, n = 761; remission, n = 701/cognitive: acute, n = 347; post-acute, n = 636; remission, n = 500.
Q26/57/88 (HCP) What symptoms does the patient most want addressed with the treatment prescribed? Baseline: PRFs who experience each group of symptoms.
Baseline: HCP PRFs mood: acute n = 1,023, post-acute n = 929, remission n = 614/physical: acute n = 994, post-acute n = 912, remission n = 683/cognitive: acute n = 894, post-acute n = 769, remission n = 467.
Q21 (Patient) Which symptoms, if any, do you feel your current treatment does not adequately treat during this phase of depression? Baseline: Patients who experience each group of symptoms.
Baseline: patients, mood: acute, n = 408; post-acute, n = 761; remission, n = 635/physical: acute, n = 407; post-acute, n = 761; remission n = 701/cognitive: acute, n = 347; post-acute, n = 636; remission, n = 500.
Q25/56/87 (HCP) Which of the following symptoms that this patient has experienced during this phase of depression can you NOT adequately treat? Baseline: PRFs who experience each group of symptoms.
Baseline: HCP PRFs, mood: acute n = 1,023, post-acute n = 929, remission, n = 614/physical: acute, n = 994; post-acute n = 912; remission, n = 683/cognition: acute n = 894; post-acute, n = 769; remission, n = 467.
HCP, health care professional; n, subset of population; PRF, patient record form.
z-tests undertaken on patient and HCP-assessed cohorts to determine statistically significant differences:
*The difference between patient and HCP cohort is statistically significant at the 95% confidence interval, **The difference between patient and HCP cohort is statistically significant at the 99% confidence interval.