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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Antiviral Res. 2019 Mar 26;166:56–65. doi: 10.1016/j.antiviral.2019.03.012

Fig. 6.

Fig. 6.

Buccal immunization with reconstituted SFD mixed MS2-L2 VLPs after 60-day storage and oral protection from HPV PsV16. Spray-freeze dried VLPs were reconstituted in PBS after 60-day storage at room temperature. The reconstituted VLPs in the presence of fresh CT/MPLA adjuvants were used to immunize mice thrice. Immunized mice were orally challenged with 7 × 106 IU of HPV PsV16. Each datum represents the average radiance of an individual mouse and the lines represent the geometric mean for each group. The P-values were determined by unpaired one-tailed t-test.