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. Author manuscript; available in PMC: 2019 May 28.
Published in final edited form as: Dev Dyn. 2011 Oct 27;241(1):69–84. doi: 10.1002/dvdy.22764

Figure 3. Lobe (L) and Serrate (Ser) are required for cell survival in developing eye imaginal disc.

Figure 3

(A) In wild-type eye imaginal disc, L (green) expression is ubiquitous. Elav (red) marks the photoreceptor neurons. (B) wild-type adult eye. (C, D) Loss of L results in the preferential loss of ventral half of the (C) developing eye imaginal disc, and (D) the adult eye. (C) Eye imaginal discs stained for Wg (green) to identify dorsal versus ventral eye imaginal disc compartment. The boundary of the eye field is as outlined in C (white) and D (black) showing preferential loss of ventral eye. (E, F) Early loss-of-function of Ser by misexpressing dominant negative form of Ser in the entire eye imaginal (Kumar and Moses, 2001; Singh and Choi, 2003) using an ey-Gal4 driver (Hazelett et al., 1998; Singh and Choi, 2003) results in complete loss of eye field both in (E) the eye imaginal disc, and (E) the adult.