FIG. 9.
Assessment of radiation-induced cardiac and renal senescence. Relative expression changes for p!giNK4a mRNA were determined by real-time qPCR in heart and kidney tissues at (panel A) 7 months (n = 5–6) and (panel B) 22 months (n = 3–5) post-TBI and compared to age-matched nonirradiated tissues. Results are expressed as relative fold change after normalization to HPRT.