Table 1.
Protein | Family | RNA-binding domains | Oligomerization | References |
---|---|---|---|---|
Celf1 | ELAV/Hu like | 3 RRMs | Yes | Bauermeister et al. (2015), Arthur et al. (2009) |
Dazl | RRM containing | 1 RRM | Yes | Heim et al. (2014), Fu et al. (2015) |
Ddx4 (Vasa) | DEAD box RNA helicase | DEAD domain | Yes | Nott et al. (2015) |
Dnd1 | RRM containing | 2 RRMs | No | Kedde et al. (2007), Koebernick et al. (2010) |
Elav1/2 | ELAV/Hu like | 3 RRMs | Yes | Cosson et al. (2006), Devaux et al. (2006) |
Hnrnpab | hnRNP/RRM | 2 RRMs | Yes | Xiang et al. (2015), Aguero et al. (2016) |
Igf2bp3 (Vera) | IMP/VICKZ | KH þ RRM | No | Deshler et al. (1997), Havin et al. (1998) |
Ptbp1 | hnRNP/RRM | 4 RRMs | No | Monie et al. (2005) |
Rbm24b | RRM containing | 1 RRM | Yes | Nijjar and Woodland (2013a) |
Rbm42b | RRM containing | 1 RRM | Yes | Nijjar and Woodland (2013a) |
Rbpms2 (Hermes) | RRM containing | 1 RRM | Yes | Heim et al. (2014), Sagnol et al. (2014) |
Staufen1 | Double-stranded RNA binding | DSRM | Yes | Martel et al. (2010) |
Velo1 (Buc) | YppG like | Predicted RNA binding C-terminal (K/R rich) | Yes | Boke et al. (2016) |
Characteristics of RNA-binding proteins involved in RNA localization and discussed in this review. The general mode of RNA binding is noted, as is the ability for self-interaction (oligomerization). All of these proteins contain IDRs either at the N- and C-termini and/or interspersed between the RNA-binding domains (our unpublished observations)