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. 2019 May 28;16(5):e1002810. doi: 10.1371/journal.pmed.1002810

Table 2. Clinical progression glioma group.

Pathology Number ΔG Time to growth (months), median (IQR) ΔV, median (IQR)
CAD VC p-Value CAD VC p-Value
Oligodendroglioma 7 7 19 (13–23) 79 (48–101) <0.001 52% (36%–72%) 163% (141%–479%) 0.001
Astrocytoma 18 14 12 (10–16) 33 (26–44) <0.001 50% (37%–76%) 155% (120%–257%) 0.001
Mixed glioma 9 8 16 (10–20) 56 (31–70) <0.001 69% (46%–116%) 286% (203%–537%) <0.001
All 34 29 14 (11–20) 44 (30–68) <0.001 57% (36%–77%) 174% (134%–342%) <0.001

ΔG: number of patients whose glioma time to growth detected by computer-assisted diagnosis (CAD) was shorter than that detected by visual comparison (VC). ΔV: percent change in tumor volume from baseline to time point of growth detection. The p-values were generated by the Mann–Whitney–Wilcoxon 2-tail test. The results of CAD were identical to that of VC in 5 patients.