Table 3. Odds ratios of at least mild or moderate depressive symptoms by patient and RA-related characteristics.
| ≥ Mild Odds Ratio (95% CI) |
≥ Moderate Odds Ratio (95% CI) |
|||
|---|---|---|---|---|
| Influence Variable | Unadjusted | Adjusted | Unadjusted | Adjusted |
| Age (1: <60, 0: ≥60) |
1.50 (1.16–1.93) |
1.78 (1.13–2.80) |
1.76 (1.31–2.37) |
2.16 (1.31–3.56) |
| Sex (0 = female, 1 = male) |
0.78 (0.59 - 1.04) |
0.93 (0.63–1.36) |
0.88 (0.62–1.25) |
0.96 (0.62–1.50) |
| Family status (family = 1, alone = 0) |
1.00 (0.74–1.34) |
1.07 (0.72–1.59) |
0.99 (0.70–1.42) |
1.20 (0.75–1.93) |
| BMI (kg/m2) (≥25 = 1, <25 = 0) |
1.49 (1.15–1.93) |
1.09 (0.77–1.55) |
1.27 (0.93–1.74) |
1.02 (0.68–1.53) |
| Education (>10 years = 1, ≤10 years = 0) |
0.97 (0.75–1.27) |
0.98 (0.70–1.38) |
0.80 (0.59–1.10) |
0.75 (0.51–1.10) |
| Employment (employed = 1, other = 0) |
1.09 (0.84–1.41) |
1.14 (0.73–1.79) |
1.22 (0.90–1.64) |
1.11 (0.68–1.82) |
| RA Duration (years) |
1.00 (0.99–1.02) |
1.00 (0.98–1.01) |
0.99 (0.97–1.00) |
0.99 (0.97–1.01) |
| DAS28 (ESR) (<2.6, ≥2.6) |
2.13 (1.61–2.80) |
1.27 (0.90–1.80) |
1.89 (1.37–2.61) |
1.34 (0.91–1.97) |
| RAID Score (≤2, >2) |
11.34 (7.94–16.21) |
10.54 (6.87–16.16) |
19.23 (8.43–43.86) |
13.61 (5.80–31.92) |
| cDMARDs (yes = 1, no = 0) |
0.90 (0.65–1.25) |
0.88 (0.57–1.37) |
0.75 (0.52–1.08) |
0.62 (0.39–1.00) |
| bDMARDs (yes = 1, no = 0) |
1.20 (0.93–1.54) |
0.99 (0.69–1.42) |
1.07 (0.79–1.44) |
0.83 (0.55–1.26) |
| Glucocorticoids medication (yes = 1, no = 0) |
1.54 (1.19–1.98) |
1.03 (0.74–1.44) |
1.50 (1.11–2.03) |
1.02 (0.70–1.49) |
| NSAID medication (yes = 1, no = 0) |
1.76 (1.35–2.30) |
1.24 (0.87–1.75) |
1.74 (1.29–2.35) |
1.42 (0.97–2.08) |
| Opiates medication (yes = 1, no = 0) |
3.03 (1.49–6.18) |
1.50 (0.64–3.48) |
2.77 (1.51–5.06) |
1.67 (0.79–3.55) |
| Comorbidity without mental illness or chronic pain (0 = no, 1 = yes) |
0.79 (0.62–1.02) |
1.03 (0.71–1.49) |
0.81 (0.60–1.09) |
1.18 (0.77–1.81) |
| Chronic pain (0 = no, 1 = yes) |
3.07 (1.86–5.08) |
3.25 (1.65–6.39) |
2.55 (1.64–3.97) |
2.90 (1.55–5.43) |
aReference category for ORs: age ≥60, female sex, DAS28 <2.6, RAID ≤2, no for each type of RA medication, and no for presence of a comorbidity without mental illness or chronic pain, no for chronic pain. Adjusted odds ratios adjusted in multiple logistic regression for other covariates in table. Abbreviations: RA = rheumatoid arthritis, DAS = Disease Activity Score, ESR = erythrocyte sedimentation rate, RAID = Rheumatoid Arthritis Impact of Disease questionnaire