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(A) Simulation snapshot at the beginning of a free growing CT26 spheroid (R = 100 μm), indicating quiescent (dark) and proliferating cells (light). (B-D) Simulation snapshots of growing CT26 spheroids at R = 120 μm during dextran application (p = 5 kPa), indicating quiescent and proliferating cells (B), individual cell pressure (C), and volume for the cells (D).
