Table 3.
Correlations between memory performance scores and hippocampal volume.
| All patients with AD | ε4+/GG- carriers |
ε4+/A-allele- carriers |
ε4-/GG- carriers | ε4-/A-allele-carriers | |
|---|---|---|---|---|---|
| TIV adjusted left hippocampal volume | |||||
| CVVLT-30 s scores | 0.525* (<0.001) |
0.769* (0.002) |
0.454* (0.023) |
0.598* (<0.001) |
0.230 (0.279) |
| CVVLT-10 min scores | 0.595* (<0.001) |
0.812* (0.001) |
0.676* (<0.001) |
0.533* (0.001) |
0.263 (0.215) |
| CVVLT-cued scores | 0.526* (<0.001) |
0.518 (0.070) |
0.574* 0.003 |
0.505* (0.002) |
0.143 (0.506) |
| TIV adjusted right hippocampal volume | |||||
| CVVLT-30 s scores | 0.554* (<0.001) |
0.837* (<0.001) |
0.606* (0.001) |
0.493* (0.003) |
0.278 (0.189) |
| CVVLT-10 min scores | 0.611* (<0.001) |
0.745* (0.003) |
0.757* (<0.001) |
0.524* (0.001) |
0.229 (0.282) |
| CVVLT-cued scores | 0.564* (<0.001) |
0.631* (0.021) |
0.665* (<0.001) |
0.467* (0.005) |
0.202 (0.506) |
Data are presented as ρ (p value); *p< 0.05; AD, Alzheimer’s disease; CVVLT, Chinese version of the Verbal Learning Test (CVVLT-30 s: words recalled after 30 seconds; CVVLT-10 min: words recalled after 10 minutes; CVVLT-cued: words recalled with cued procedures); ε4+/GG-carriers: apolipoprotein E (APOE)-ε4 carriers with fibroblast growth factor 1 (FGF1)-rs34011-GG genotype; ε4+/A-allele-carriers: APOE-ε4 carriers with FGF1-rs34011-A-allele genotype; ε4-/GG-carriers: APOE-ε4 non-carriers with FGF1-rs34011-GG genotype; ε4-/A-allele-carriers: APOE-ε4 non-carriers with FGF1-rs34011-A-allele genotype; TIV, total intracranial volume.