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. 2019 May 2;4(9):e98101. doi: 10.1172/jci.insight.98101

Figure 4. CBAs attenuate HDM-induced inflammatory cytokines, chemokines, and the UPR.

Figure 4

(A–E) Quantification of cytokines/chemokines by ELISAs from lung homogenates. Kruskal-Wallis, 2-stage linear step-up procedure of Benjamini, Krieger, and Yekutieli. Six comparisons, all with the HDM plus DMSO group. *P < 0.05 vs. PBS plus DMSO group; #P < 0.05 vs. HDM plus DMSO group; ns, not significant. PBS and HDM plus DMSO n = 6 mice/group from 2 experiments; HDM plus TCCA/βM/GM/AβM/GnβM n = 10 mice/group from 2 experiments. (F) Expression of UPR markers from lung homogenates of HDM-sensitized and -challenged mice treated with AβM, TCCA, or DMSO (vehicle); n = 4 representative lung lysates for each group. Densitometry in Supplemental Figure 3. ns, not significant. Error bars represent ± SEM.