Table 1. Diagnostic accuracy of the tuberculosis culture (TB-CX) test, Xpert MTB/RIF test compared to the Lӧwenstein Jensen (LJ) culture method.
Assay | Sensitivity | Specificity | PPV | NPV | Kappa | Test Efficiency | P-value | |||
---|---|---|---|---|---|---|---|---|---|---|
Solid LJ culture | ||||||||||
TB-CX Test | Positive | Negative | Total | |||||||
Positive | 73 | 1 | 74 | |||||||
Negative | 5 | 58 | 64 | 94% | 98% | 99% | 92% | 0.91 | 0.96 | < 0.001 |
Total | 78 | 59 | 137 | |||||||
GeneXpert | ||||||||||
Positive | 75 | 12 | 87 | |||||||
Negative | 3 | 47 | 50 | 96% | 80% | 87% | 98% | 0.80 | 0.89 | < 0.001 |
Total | 78 | 59 | 137 |
Note: PPV = positive predictive value, NPV = negative predictive value, LJ = Lӧwenstein-Jensen, the kappa (k) value is a measure of test reliability, interpreted as follows: <0.4 = poor; 0.4–0.75 = fair to good; >0.75 = strong.