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. 2019 May 28;14(5):e0215679. doi: 10.1371/journal.pone.0215679

Table 1. Diagnostic accuracy of the tuberculosis culture (TB-CX) test, Xpert MTB/RIF test compared to the Lӧwenstein Jensen (LJ) culture method.

Assay Sensitivity Specificity PPV NPV Kappa Test Efficiency P-value
Solid LJ culture
TB-CX Test Positive Negative Total
Positive 73 1 74
Negative 5 58 64 94% 98% 99% 92% 0.91 0.96 < 0.001
Total 78 59 137
GeneXpert
Positive 75 12 87
Negative 3 47 50 96% 80% 87% 98% 0.80 0.89 < 0.001
Total 78 59 137

Note: PPV = positive predictive value, NPV = negative predictive value, LJ = Lӧwenstein-Jensen, the kappa (k) value is a measure of test reliability, interpreted as follows: <0.4 = poor; 0.4–0.75 = fair to good; >0.75 = strong.