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. 2019 May 28;14(5):e0215679. doi: 10.1371/journal.pone.0215679

Table 4. Comparison the LJ indirect proportional method (n = 72), the tuberculosis culture (TB-CX) test (n = 70) with Xpert MTB/RIF assay for detection of rifampin drug resistance.

XpertMTB/RIF Agreement kappa value P value
Susceptible Resistance Concordant Discordant
LJ IPM (RIF)
Susceptible 49 (98%) 2 (9%) 69(96%) 3(4%) 0.87 < 0.001
Resistance 1 (2%) 20 (91%)
TB-CX test
Susceptible 6 (12%) 0 (0%) 27(39%) 43(61%) 0.28 < 0.001
Resistance 43 (88%) 21(100%)

Note: LJ IPM: LJ indirect proportional DST, the kappa (k) value is a measure of test reliability, interpreted as follows: <0.4 = poor; 0.4–0.75 = fair to good; >0.75 = strong.