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. Author manuscript; available in PMC: 2019 May 28.
Published in final edited form as: Pediatr Blood Cancer. 2017 Jun 23;64(12):10.1002/pbc.26689. doi: 10.1002/pbc.26689

TABLE 3.

Blood count measurements at Personal best HbF, study initiation month 0 (M0), and at completion (M6) by the study group

Parameters At Personal best HbF
Study month 0
Study month 6a
Intervention
n = 18
Control
n = 10
P value Intervention
n = 18
Control
n = 10
P value Intervention
n = 16
Control
n = 8
P valueb
HU dose 24.9 ± 4.8   23.8 ± 4.6 0.52 25.9 ± 3.9 21.7 ± 4.4 0.03 24.3 ± 7.6 22.5 ± 3.5 0.11
Hb  8.9 ± 1.6   9.1 ± 0.7 0.70  8.6 ± 1.3  9.3 ± 1.3 0.25  8.9 ± 1.2  9.5 ± 1.8 0.44
MCV 96.9 ± 11.7 101.1 ± 10.2 0.35 94.5 ± 13.0 86.8 ± 30.8 0.94 98.0 ± 11.3 89.0 ± 35.7 0.76
ARC  258 ± 181   204 ± 69 0.76  321 ± 183  307 ± 141 0.94  253 ± 133  248 ± 143 0.71
WBC 10.1 ± 3.8   9.1 ± 3.0 0.64  9.5 ± 2.8 10.5 ± 3.8 0.54  9.0 ± 2.7  7.9 ± 2.6 0.26
ANC  4.7 ± 2.0   4.7 ± 3.0 0.60  4.5 ± 1.9  4.0 ± 1.9 0.59  3.2 ± 2.0  3.6 ± 1.5 0.71
Platelets  474 ± 338   439 ± 175 0.54  485 ± 262  350 ± 159 0.36  453 ± 248  438 ± 179 0.92

PB, Personal best HbF.

a

Intervention group: one withdrawal and one with multiple transfusions; Control group: two withdrawals.

b

Wilcoxon rank sum. Bold P value means statistical significance.