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. Author manuscript; available in PMC: 2019 Dec 17.

Published in final edited form as: Chem Res Toxicol. 2018 Nov 19;31(12):1293–1304. doi: 10.1021/acs.chemrestox.8b00170

Table 1.

Carboplatin Cell Line Sensitivities and Monoadduct AUC Levels

carboplatin			oxaliplatin
status	cell line	IC₅₀ (μM)	sensitivity	cell line	IC₅₀ (μM)
sensitive IC₅₀ < 100 μM	Hs 578T	43.0	sensitive IC₅₀ < 10 μM	MCF7	1.03
	MDA- MB- 468	44.0		T-47D	2.35
	MDA- MB- 468
	BT-549	68.3		BT-549	6.71
	MCF7	136		MDA- MB- 468	150
resistant IC₅₀ > 100 μM	MDA- MB- 231 T-47D	248	resistant IC₅₀ > 10 μM	Hs 578T MDA- MB- 231	177

		250			199