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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: NMR Biomed. 2017 Nov 29;31(10):e3840. doi: 10.1002/nbm.3840

FIGURE 5.

FIGURE 5

H&E staining (A, D), T2w RARE scan (B, E) and viscoelastic modulus map (in kPa; C, F), all in the same location in two different mice 4 weeks after tumor implantation. The arrowheads in the H&E stained sections indicate areas that were completely destroyed (D, arrowheads) or show larger cracks (A, arrowheads) after the staining procedure. These areas coincide with soft areas on the elastograms (C, F, arrowheads). We hypothesize that this damage occurred due to loss off necrotic tissue during the staining procedure. One animal presented with patchy intratumoral hemorrhage, corresponding to a softer region on the viscoelastic modulus map (asterisks, A-C).