TABLE 1.
Longitudinal evaluation of viscoelastic modulus and shear wave speed. The values were obtained in a control ROI and ROIs covering the tumors in week 2 – 4 after tumor implantation. The percentage difference was calculated between a particular time point with respect to the immediate preceding time point as well as with respect to the control. SD = standard deviation.
| shear wave speed Cs (m/s) mean (SD) |
viscoelastic modulus |G*| (kPa) mean (SD) |
phase angle Y mean (SD) |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| control | week 2 | week 3 | week 4 | control | week 2 | week 3 | week 4 | control | week 2 | week 3 | week 4 | |
| mouse 1 | 3.38 (0.39) |
3.39 (0.23) |
2.89 (0.43) |
2.51 (0.56) |
10.33 (2.04) |
10.07 (1.52) |
7.93 (2.57) |
6.21 (2.7) |
0.37 (0.13) | 0.45 (0.07) | 0.34 (0.14) | 0.29 (0.12) |
| mouse 2 | 3.35 (0.38) |
2.87 (0.34) |
2.80 (0.58) |
2.45 (0.74) |
10.23 (2.31) |
7.85 (1.53) |
7.57 (3.8) |
6.27 (4.27) |
0.34 (0.13) | 0.27 (0.11) | 0.32 (0.17) | 0.27 (0.14) |
| mouse 3 | 3.13 (0.48) |
3.01 (0.37) |
2.80 (0.58) |
- | 9.15 (2.47) |
8.30 (1.72) |
7.86 (3.58) |
- | 0.34 (0.12) | 0.30 (0.16) | 0.22 (0.13) | - |
| mouse 4 | 3.43 (0.60) |
2.85 (0.31) |
- | - | 10.56 (3.27) |
7.56 (1.59) |
- | - | 0.40 (0.18) | 0.31 (0.13) | - | - |
| mouse 5 | - | 2.93 (0.38) |
2.81 (0.48) |
- | - | 8.15 (1.89) |
7.63 (2.65) |
- | - | 0.33 (0.15) | 0.28 (0.13) | - |
| average | 3.32 (0.13) |
3.01 (0.22) |
2.83 (0.04) |
2.48 (0.04) |
10.07 (0.63) |
8.39 (0.98) |
7.75 (0.17) |
6.24 (0.04) |
0.36 (0.03) | 0.34 (0.07) | 0.29 (0.06) | 0.28 (0.01) |
| Percentage difference (%) | ||||||||||||
| vs. immediate previous time point | - | 9.34 | 6.00 | 12.37 | - | 16.68 | 7.63 | 19.48 | - | 5.5 | 13.89 | 3.45 |
| vs. control | - | 9.34 | 14.76 | 25.30 | - | 16.68 | 23.04 | 37.74 | - | 5.5 | 19.44 | 22.22 |