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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Psychiatry Res. 2019 Apr 16;276:60–68. doi: 10.1016/j.psychres.2019.04.016

Table 6.

Multivariate Latent Growth Curve Model with Positive Symptoms Unstandardized Estimates

Multivariate Covariances
Parameters Estimates SE p-value
FB level and PS level 7.32 3.52 < .05
FB level and PS change −6.21 3.91 .11
PS level and FB change −0.34 4.13 .94
FB change and PS change 4.69 4.75 .32
FB and PS Residuals 2.90 1.22 < .05
Family Burden Model Positive Symptoms Model
Parameters Estimates SE p-value Estimates SE p-value
Latent Growth Curve
Level factor mean 43.30 2.16 <.01 11.10 0.54 <.01
Level factor residual 142.76 18.21 <.01 7.14 1.21 <.01
Change factor mean −13.67 2.90 <.01 −2.35 0.66 <.01
Change factor residual 125.14 27.96 <.01 5.33 1.67 <.01
Level and change covariance −76.62 18.55 <.01 −2.42 1.13 <.05
Indicator residual variance 46.71 4.26 <.01 6.48 0.42 <.01
Time-Varying Covariate Effects
MA at Baseline −2.15 3.99 .59 0.32 0.95 .74
MA at 6 months −0.28 2.98 .93 0.37 0.84 .66
MA at 12 months 1.68 3.46 .63 1.30 0.76 .09
MA at 18 months 5.30 3.04 .08 0.10 0.92 .92
MA at 24 months 5.05 4.14 .22 0.09 0.98 .93
DS at Baseline −0.22 0.22 .32 0.18 0.05 <.01
DS at 6 months 0.62 0.22 <.01 0.25 0.05 <.01
DS at 12 months 0.66 0.26 <.05 0.23 0.07 <.01
DSatl 8 months 0.57 0.29 .05 0.29 0.07 <.01
DS at 24 months −0.16 0.46 .73 0.12 0.08 .13
Time-Invariant Covariate Effects
Gender → level factor 1.64 2.09 .43 −0.60 0.52 .25
Age → level factor −0.20 0.19 .30 0.06 0.05 .20
DUP → level factor 0.01 0.01 .94 0.01 0.01 .60
FP → level factor 3.35 2.00 .09 0.45 0.50 .37
Gender → change factor 1.15 2.66 .67 0.37 0.60 .54
Age → change factor −0.09 0.23 .71 −0.01 0.05 .98
DUP → change factor 0.01 0.01 .51 0.01 0.01 <.05
FP → change factor −0.53 2.64 .84 −0.50 0.59 .40

Note: Model fit: χ2(170) = 264.07; RMSEA = 0.04 [CI: 0.034, 0.054]; TLI = 0.83; CFI = 0.85. FB = Family Burden, PS = Positive Symptoms, MA = Medication Adherence, DS = Depressive Symptoms, FP = Family Psychoeducation, DUP = Duration of Untreated Psychosis