Table 2.

PRSice best fit for Stroke risk, HTN and T2DM for the two GENISIS phenotypes (ΔNIHSS and baseline NIHSS) in each subpopulation (Trans-ethnic, Non-Hispanic White and Non-Hispanic Non-Finnish White)

Population	Phenotype	P-Value	Variance	SNPs
		Stroke Risk (MEGASTROKE)
Trans-Ethnic	Delta	0.154	<0.001	7,907
	Baseline	0.238	<0.001	27,378
Non-Hispanic White	Delta	0.055	<0.001	1,003
	Baseline	0.006	0.003	136,023
Non-Hispanic Non-Finnish White	Delta	0.014	0.003	1,003
	Baseline	0.030	0.003	136,023
		Type 2 Diabetes Mellitus (Diagram)
Non-Hispanic White	Delta	0.007	0.003	4,618
	Baseline	0.447	<0.001	268
Non-Hispanic Non-Finnish White	Delta	0.024	0.003	4,618
	Baseline	0.530	<0.001	268
		Hypertension (CHARGE)
Non-Hispanic White	Delta	0.066	0.001	1,257
	Baseline	0.027	0.002	6
Non-Hispanic Non-Finnish White	Delta	0.057	0.002	205
	Baseline	0.103	0.001	205

Nominally significant p-values are in bold